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Magnesium Sulfate A Common Medicine For Obstetrics
- Oct 24, 2017 -

Magnesium Sulfate sulfate is a commonly used medicine in obstetrics, which is used in the prevention and treatment of hypertensive disorders and preterm birth in pregnancy. Today we will combine the latest clinical guidelines to summarize the application of Magnesium Sulfate sulfate in obstetrics.

Magnesium Sulfate sulfate and treatment of premature delivery

1. Mechanism: The high concentration of Magnesium Sulfate ions directly acting on uterine smooth muscle cells, antagonistic to calcium ions on uterine contraction activity, has a better inhibition of uterine contraction.

2. Usage: 25% of Magnesium Sulfate sulfate is added to $number ml in 5% of the glucose solution, in 30-60 minutes after intravenous drip, and later in the g/h dosage maintained, the daily total of not more than G.

3. It should be recalled that there was no consensus on the timing and dosage of Magnesium Sulfate sulfate, and the Canadian Association of Obstetrics and Gynecology (SOGC) guidelines recommended 32 weeks before pregnancy, after uterine dilatation, and with a load dose of 4.0 g intravenous drip, min drop, and then 1 g/h to maintain the delivery. The ACOG guideline does not have a specific dose recommendation, but it is recommended that the Magnesium Sulfate sulfate time be applied not exceeding the H.

4. Note: The process of drug use must monitor the concentration of Magnesium Sulfate ions, pay close attention to respiratory, knee reflex and urine volume. If the respiration is less than 16 times/min, the urine quantity is less than the ml/h, the knee reflex disappears, should stop the medicine immediately, and give the calcium agent antagonistic resistance. Because the blood Magnesium Sulfate ion concentration which suppresses the uterine contraction is close to the toxic concentration, the renal insufficiency, the muscle weakness, the heart disease patient disables.


Magnesium Sulfate sulfate is a commonly used medicine in obstetrics, which is used in the prevention and treatment of hypertensive disorders and preterm birth in pregnancy. Today we will combine the latest clinical guidelines to summarize the application of Magnesium Sulfate sulfate in obstetrics.

1. Mechanism: The high concentration of Magnesium Sulfate ions directly acting on uterine smooth muscle cells, antagonistic to calcium ions on uterine contraction activity, has a better inhibition of uterine contraction.

2. Usage: 25% of Magnesium Sulfate sulfate is added to $number ml in 5% of the glucose solution, in 30-60 minutes after intravenous drip, and later in the g/h dosage maintained, the daily total of not more than G.

3. It should be recalled that there was no consensus on the timing and dosage of Magnesium Sulfate sulfate, and the Canadian Association of Obstetrics and Gynecology (SOGC) guidelines recommended 32 weeks before pregnancy, after uterine dilatation, and with a load dose of 4.0 g intravenous drip, min drop, and then 1 g/h to maintain the delivery. The ACOG guideline does not have a specific dose recommendation, but it is recommended that the Magnesium Sulfate sulfate time be applied not exceeding the H.

4. Note: The process of drug use must monitor the concentration of Magnesium Sulfate ions, pay close attention to respiratory, knee reflex and urine volume. If the respiration is less than 16 times/min, the urine quantity is less than the ml/h, the knee reflex disappears, should stop the medicine immediately, and give the calcium agent antagonistic resistance. Because the blood Magnesium Sulfate ion concentration which suppresses the uterine contraction is close to the toxic concentration, the renal insufficiency, the muscle weakness, the heart disease patient disables.